Space Travel Weakens the Heart, New Study Finds

The International Space Station (ISS) in orbit. Credit: NASA

It’s no secret that spending extended periods in space takes a toll on the human body. For years, NASA and other space agencies have been researching the effects of microgravity on humans, animals, and plants aboard the International Space Station (ISS). So far, the research has shown that being in space for long periods leads to muscle atrophy, bone density loss, changes in vision, gene expression, and psychological issues. Knowing these effects and how to mitigate them is essential given our future space exploration goals, which include long-duration missions to the Moon, Mars, and beyond.

However, according to a recent experiment led by researchers at Johns Hopkins University and supported by NASA’s Johnson Space Center, it appears that heart tissues “really don’t fare well in space” either. The experiment consisted of 48 samples of human bioengineered heart tissue being sent to the ISS for 30 days. As they indicate in their paper, the experiment demonstrates that exposure to microgravity weakens heart tissue and weakens its ability to maintain rhythmic beats. These results indicate that additional measures must be taken to ensure humans can maintain their cardiovascular health in space.

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Astronauts’ Muscle Loss Mimics Age-Related Muscle Loss

Researchers grew muscle cells on tiny chips then sent them to the ISS to study them. Researchers hope to develop drugs to help astronauts combat muscle atrophy during space flight. Image Credit: NASA. CC BY-SA

One of the hazards astronauts must contend with is muscle loss. The more time they spend in a microgravity environment, the more muscle loss they suffer. Astronauts use exercise to counter the effects of muscle atrophy, but it’s not a perfect solution. Researchers want to develop drugs to help, and understanding the muscle-loss process in space is a critical first step.

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A Capsule With Antiviral Drugs Grown in Space Returns to Earth

The W-1 capsule landing at the Utah Test and Training Range. Credit: Vargas Space Industries

On Wednesday, February 21st, at 01:40 p.m. PST (04:40 p.m. EST), an interesting package returned to Earth from space. This was the capsule from the W-1 mission, an orbital platform manufactured by California-based Varda Space Industries, which landed at the Utah Test and Training Range (UTTR). Even more interesting was the payload, which consisted of antiviral drugs grown in the microgravity environment of Low Earth Orbit (LEO). The mission is part of the company’s goal to develop the infrastructure to make LEO more accessible to commercial industries.

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How Can Astronauts Maintain Their Bodies With Minimal Equipment?

NASA astronauts Bob Hines and Kjell Lindgren work out on the Advanced Resistive Exercise Device (ARED). Credits: NASA

Decades of research aboard the International Space Station (ISS) and other spacecraft in Low Earth Orbit (LEO) have shown that long-duration stays in microgravity will take a toll on human physiology. Among the most notable effects are muscle atrophy and bone density loss and effects on eyesight, blood flow, and cardiovascular health. However, as research like NASA’s Twin Study showed, the effects extend to organ function, psychological effects, and gene expression. Mitigating these effects is vital for future missions to the Moon, Mars, and other deep-space destinations.

To reduce the impact of microgravity, astronauts aboard the ISS rely on a strict regiment of resistance training, proper diet, and cardiovascular exercise to engage their muscles, bones, and other connective tissues that comprise their musculoskeletal systems. Unfortunately, the machines aboard the ISS are too large and heavy to bring aboard spacecraft for long-duration spaceflights, where space and mass requirements are limited. To address this, NASA is investigating whether exercise regimens that rely on minimal or no equipment could provide adequate physical activity.

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What Can Be Done to Help Astronaut Vision in Space?

Astronauts Kate Rubins (left) and Jeff Williams (right) looking out of the ISS' cupola at a SpaceX Dragon supply spacecraft. Until recently, the effects of long-duration missions on eyesight was something of a mystery. Credit: NASA

Spaceflight takes a serious toll on the human body. As NASA’s Twin Study demonstrates, long-duration stays in space lead to muscle and bone density loss. There are also notable effects on the cardiovascular, central nervous, and endocrine systems, as well as changes in gene expression and cognitive function. There’s also visual impairment, known as Spaceflight-Associated Neuro-ocular Syndrome (SANS), which many astronauts reported after spending two months aboard the International Space Station (ISS). This results from increased intracranial pressure that places stress on the optic nerve and leads to temporary blindness.

Researchers are looking for ways to diagnose and treat these issues to prepare for future missions that will involve long-duration stays beyond Earth and transits in deep space. A cross-disciplinary team of researchers led by the University of Western Australia (UWA) has developed a breakthrough method for measuring brain fluid pressure that could reduce the risk of SANS for astronauts on long-duration spaceflights. This research could have applications for the many efforts to create a human presence on the Moon in this decade and crewed missions to Mars in the next.

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Fire Acts Strangely in Microgravity. Astronauts Have Lit More Than 1,500 Fires on the Space Station to Figure Out Why

Ever since childhood, we were all told to never play with fire. Despite it being relevant to our everyday lives, to include heating our homes and water, cooking our food, producing electricity, and more, fire is extremely dangerous. We were all indoctrinated more with how to put out fires instead of how to start one. We’ve all been told about its destructive properties if mishandled, and that fire needs to be controlled. One of the perks of adulthood, and especially being a scientist, is you get paid to play with fire. Despite fire’s complexities, there’s still a lot we don’t know about its behavior. With more and more of humanity traveling to space and living in microgravity, it’s important to learn about how fire behaves in this unique environment to better prepare ourselves for worst case scenarios. But what if we could also control fire so it’s not as dangerous and less destructive to the environment back here on Earth?

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Spacefaring Worms Show How Gravity Affects Genes

Image of the ISS that shows the Beta material covering the outside.

In this decade and the next, humanity is poised to go to space like never before. National space agencies will be sending astronauts back to the Moon for the first time since the Apollo Era, private launch services will spearhead the commercialization of Low Earth Orbit (LEO), missions to the outer Solar System will search for evidence of extraterrestrial life, and crewed missions to Mars are on the horizon.

In preparation for this, a considerable amount of research is being done aboard the International Space Station (ISS) to determine how extended periods of time in space can affect living beings on the genetic level. In a recent experiment, a team of researchers from the University of Exeter conducted an analysis of worms on the ISS and noted “subtle changes” in their genetic makeup.

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This is Foam, Made in Space

An early image from the ESA's Foam-Coarsening on the ISS. Image Credit: ESA

Say hello to Space Foam.

The ESA has a science lab on the International Space Station called Columbus. Inside that lab is the Fluid Science Laboratory, dedicated to studying the behaviour of fluids in microgravity. Currently, that lab is being used to study a substance most of us probably don’t spend much time thinking about: foam.

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Cancer Seems to Have Trouble Spreading in Microgravity

The International Space Station (ISS), seen here with Earth as a backdrop. Credit: NASA
The International Space Station (ISS), seen here with Earth as a backdrop. Credit: NASA

There are a number of health risks that come with going to space. Aside from the increased exposure to solar radiation and cosmic rays, there are the notable effects that microgravity can have on human physiology. As Scott Kelly can attest, these go beyond muscle and bone degeneration and include diminished organ function, eyesight, and even changes at the genetic level.

Interestingly enough, there are also a number of potential medical benefits to microgravity. Since 2014, Dr. Joshua Choi, a senior lecturer in biomedical engineering at the University of Technology Sydney, has been investigating how microgravity affects medicine and cells in the human body. Early next year, he and his research team will be traveling to the ISS to test a new method for treating cancer that relies on microgravity.

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Astronauts Try Mixing Concrete in Space

International Space Station. Credit: NASA
International Space Station. Credit: NASA

What sounds like a slap-stick comedy shtick is actually solid science. With so much of humanity’s space-faring future involving habitats, other structures, and a permanent presence on the Moon and Mars, mixing concrete in space is serious business. NASA has a program of study called MICS, (Microgravity Investigation of Cement Solidification) which is examining how we might build habitats or other structures in microgravity.

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